NADPH oxidase 4 (NOX4) Rabbit Polyclonal Antibody
CNY 5,808.00
Cited in 6 publications. |
CNY 300.00
CNY 1,430.00
CNY 9,998.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | NOX4 antibody was raised against a 14 amino acid peptide near the amino terminus of human NOX4. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | NOX4 antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | Predicted: 64 kDa; Observed: 68 kDa |
Gene Name | NADPH oxidase 4 |
Database Link | |
Background | The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX4 is is expressed in multiple tissues and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) (2,3). Unlike other NOX proteins, NOX4 does not require cytosolic subunits and thus is constitutively active (4). The function of NOX4 remains unclear as it plays both protective and deleterious roles in cellular metabolism. |
Synonyms | p150; VPS15 |
Reference Data |
Citations (6)
The use of this Antibodies has been cited in the following citations: |
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Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice
,null,
Nature Communications
,PubMed ID 36871047
[NOX4]
|
Histone deacetylase 3 inhibition alleviates type 2 diabetes mellitus-induced endothelial dysfunction via Nrf2
,Huang, S;Chen, G;Sun, J;Chen, Y;Wang, N;Dong, Y;Shen, E;Hu, Z;Gong, W;Jin, L;Cong, W;,
Cell communication and signaling : CCS
,PubMed ID 33736642
[NOX4]
|
Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression
,Li, Y;Ma, G;Lv, Y;Su, J;Li, G;Chen, X;,
Molecules
,PubMed ID 31117291
[NOX4]
|
Nox4 and soluble epoxide hydrolase synergistically mediate homocysteine-induced inflammation in vascular smooth muscle cells
,Liu, X;Qin, Z;Liu, C;Song, M;Luo, X;Zhao, H;Qian, D;Chen, J;Huang, L;,
Vascul. Pharmacol.
,PubMed ID 30610956
[NOX4]
|
Hydrogen sulfide alleviates uranium-induced rat hepatocyte cytotoxicity via inhibiting Nox4/ROS/p38 MAPK pathway
,Yi, J;Yuan, Y;Zheng, J;Zhao, T;,
J. Biochem. Mol. Toxicol.
,PubMed ID 30368988
[NOX4]
|
NADPH oxidase NOX4 is a critical mediator of BRAFV600E-induced down regulation of the sodium iodide symporter in papillary thyroid carcinomas
,Azouzi, N;Cailloux, J;Cazarin, JM;Knauf, JA;Cracchiolo, J;Al Ghuzlan, A;Hartl, D;Polak, M;Carre, A;El Mzibri, M;Filali-Maltouf, A;Al Bouzidi, A;Schlumberger, M;Fagin, JA;Ameziane-El-Hassani, R;Dupuy, C;,
Antioxid. Redox Signal.
,PubMed ID 27401113
[NOX4]
|
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