MALT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	MALT1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 91 kDa; Observed: 96 kDa
Gene Name	MALT1 paracaspase
Database Link	NP_006776 Entrez Gene 10892 Human UniProt ID Q9UDY8
Background	MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4).
Synonyms	LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1
Reference Data

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