Quiescin Q6 (QSOX1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	QSOX1 antibody was raised against a 17 amino acid peptide near the center of human QSOX1.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	QSOX1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 65, 82 kDa; Observed: 66 kDa
Gene Name	quiescin sulfhydryl oxidase 1
Database Link	NP_002817 Entrez Gene 5768 Human UniProt ID O00391
Background	The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation (1). The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia (2) and appears to protect cells against oxidative stress-induced apoptosis (3).
Synonyms	CFC3; MAPKK1; MEK1; MKK1; PRKMK1
Reference Data

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