S1PR2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	S1PR2 antibody was raised against an 16 amino acid peptide near the carboxy terminus of human S1PR2.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	S1PR2 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 39 kDa; Observed: 50 kDa
Gene Name	sphingosine-1-phosphate receptor 2
Database Link	NP_004221 Entrez Gene 9294 Human UniProt ID O95136
Background	The Sphingosine 1-phosphate receptor 2 (S1PR2) protein was initially identified as G-protein coupled receptor thought to be involved in development (1) and was found to mediate sphingosine 1-phosphate (SPP)-induced cell rounding and neurite retraction (2). S1PR2 and the related protein S1PR3 (also known as EDG3) are also thought to mediate the SPP-induced cell proliferation, survival, and related signaling events (3). S1PR2 has also been found to be key regulator in acute vascular inflammation and may be a novel therapeutic target for vascular disorders (4).
Synonyms	ARHI; NOEY2
Reference Data

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