Lamin B1 (LMNB1) Rabbit Polyclonal Antibody
CAT#: TA349381S
Rabbit Polyclonal Anti-LMNB1 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1000-5000 WB positive control: Hela and HT-29 cells, human fetal liver and testis tissue, 231 and K562 cells, human bladder transitional cells carcinoma tissue IHC: 100-300 Positive control: Human tonsil Predicted cell location: Nucleus and Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human LMNB1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 67 kDa |
Gene Name | lamin B1 |
Database Link | |
Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). |
Synonyms | ADLD; LMN; LMN2; LMNB |
Reference Data |
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