MAD1 (MAD1L1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela, 231, hepG2 and Raji cells IHC: 25-100 Positive control: Human brain Predicted cell location: Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human MAD1L1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	83 kDa
Gene Name	MAD1 mitotic arrest deficient like 1
Database Link	NP_003541 Entrez Gene 17120 MouseEntrez Gene 8379 Human UniProt ID Q9Y6D9
Background	MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
Synonyms	MAD1; PIG9; TP53I9; TXBP181
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle

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