ARHGEF1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human ARHGEF1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Rho guanine nucleotide exchange factor 1
Database Link	NP_945328 Entrez Gene 16801 MouseEntrez Gene 60323 RatEntrez Gene 9138 Human UniProt ID Q92888
Background	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Synonyms	GEF1; LBCL2; LSC; P115-RHOGEF; SUB1.5
Reference Data
Protein Pathways	Regulation of actin cytoskeleton, Vascular smooth muscle contraction

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