GAB1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human GAB1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	GRB2 associated binding protein 1
Database Link	NP_002030 Entrez Gene 14388 MouseEntrez Gene 2549 Human UniProt ID Q13480
Background	The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	GRB2-associated binding protein 1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	ErbB signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

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