ITLN1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1000-5000 WB positive control: Human fetal intestine tissue
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human ITLN1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35 kDa
Gene Name	intelectin 1
Database Link	NP_060095 Entrez Gene 16429 MouseEntrez Gene 55600 Human UniProt ID Q8WWA0
Background	Intelectin-1 also known as the intestinal lactoferrin receptor is a protein that in humans is encoded by the ITLN1 gene.Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin. Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.
Synonyms	hIntL; HL-1; HL1; INTL; ITLN; LFR; omentin
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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