SENP5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse testis tissue, 293T cell, K562 and NIH/3T3 cell, Mouse brain tissue lysates
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human SENP5
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	87 kDa
Gene Name	SUMO1/sentrin specific peptidase 5
Database Link	NP_689912 Entrez Gene 320213 MouseEntrez Gene 205564 Human UniProt ID Q96HI0
Background	The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
Synonyms	DKFZp564O1016; FLJ42398; MGC27076
Reference Data
Protein Families	Druggable Genome, Protease

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