TPSB2 Rabbit Polyclonal Antibody

CAT#: TA350528S

Rabbit Polyclonal Anti-TPSB2 Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
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Transient overexpression lysate of tryptase beta 2 (gene/pseudogene) (TPSB2)
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 200-1000
WB positive control: Human fetal muscle tissue lysate
IHC: 25-100
Positive control: Human liver cancer
Predicted cell location: Secreted
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name tryptase beta 2 (gene/pseudogene)
Background Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Synonyms TPS2; tryptaseB; tryptaseC
Reference Data
Protein Families Druggable Genome, Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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