HCN4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human HCN4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	hyperpolarization activated cyclic nucleotide gated potassium channel 4
Database Link	NP_005468 Entrez Gene 59266 RatEntrez Gene 330953 MouseEntrez Gene 10021 Human UniProt ID Q9Y3Q4
Background	This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
Synonyms	SSS2
Reference Data
Protein Families	Druggable Genome, Ion Channels: Cyclic nucleotide gated, Transmembrane

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