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HP1 gamma (CBX3) Rabbit Polyclonal Antibody
CAT＃: TA350694S
Rabbit Polyclonal Anti-CBX3 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: A375 and Raji cells, human fetal brain tissue IHC: 50-200 Positive control: Human gasrtic cancer Predicted cell location: Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CBX3 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 21 kDa |
| Gene Name | chromobox 3 |
| Database Link | |
| Background | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. |
| Synonyms | HECH; HP1-GAMMA; HP1Hs-gamma |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
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