Mucin 5AC (MUC5AC) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human MUC5AC
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	mucin 5AC, oligomeric mucus/gel-forming
Database Link	NP_059981 Entrez Gene 4586 Human UniProt ID P98088
Background	Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Synonyms	gastric; gastric mucin; gel-forming; MUC5; mucin 5; mucin 5AC; oligomeric mucus; subtypes A and C; tracheobronchial; tracheobronchial mucin
Reference Data
Protein Families	Druggable Genome

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