ANGPTL5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 20-100 Positive control: Human liver cancer Predicted cell location: Cell membrane and Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human ANGPTL5
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	angiopoietin like 5
Database Link	NP_835228 Entrez Gene 253935 Human UniProt ID Q86XS5
Background	Angptl5 (angiopoietin-like 5) is a 388 amino acid secreted protein that contains one fibrinogen C-terminal domain and is primarily expressed in adult heart tissue. The gene encoding Angptl5 maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia.
Synonyms	angiopoietin-like 5; fibrinogen-like
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

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