SMURF1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human SMURF1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SMAD specific E3 ubiquitin protein ligase 1
Database Link	NP_851994 Entrez Gene 75788 MouseEntrez Gene 57154 Human UniProt ID Q9HCE7
Background	This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	KIAA1625
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis, TGF-beta signaling pathway, Ubiquitin mediated proteolysis

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