LATS2 Rabbit Polyclonal Antibody

CAT#: TA350766

Rabbit Polyclonal Anti-LATS2 Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (2)
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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 25-100
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide of human LATS2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name large tumor suppressor kinase 2
Background This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Synonyms KPM
Reference Data
Protein Families Druggable Genome, Protein Kinase
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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