MEKK2 (MAP3K2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ELISA: 1000-2000, IHC: 25-100
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human MAP3K2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	mitogen-activated protein kinase kinase kinase 2
Database Link	NP_006600 Entrez Gene 26405 MouseEntrez Gene 10746 Human UniProt ID Q9Y2U5
Background	The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Synonyms	MEKK2; MEKK2B
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Gap junction, GnRH signaling pathway, MAPK signaling pathway

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