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KCNMB4 Rabbit Polyclonal Antibody
CAT＃: TA351322S
Rabbit Polyclonal Anti-KCNMB4 Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Mouse brain tissue IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human KCNMB4 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 24 kDa |
| Gene Name | potassium calcium-activated channel subfamily M regulatory beta subunit 4 |
| Database Link | |
| Background | MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. |
| Synonyms | beta member 4; calcium-activated potassium channel beta 4 subunit; large conductance calcium-dependent potassium ion channel beta 4 subunit; potassium large conductance calcium-activated channel; subfamily M |
| Reference Data | |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Protein Pathways | Vascular smooth muscle contraction |
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