PAPP A (PAPPA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PAPPA
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	pappalysin 1
Database Link	NP_002572 Entrez Gene 5069 Human UniProt ID Q13219
Background	This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
Synonyms	ASBABP2; DIPLA1; IGFBP-4ase; PAPA; PAPP-A; PAPPA1
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein

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