PGRPS (PGLYRP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PGLYRP1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	peptidoglycan recognition protein 1
Database Link	NP_005082 Entrez Gene 21946 MouseEntrez Gene 8993 Human UniProt ID O75594
Background	Peptidoglycan recognition protein is a protein that in humans is encoded by the PGLYRP1gene. Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Synonyms	PGLYRP; PGRP; PGRP-S; PGRPS; TAG7; TNFSF3L
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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