SLIT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human SLIT1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	slit guidance ligand 1
Database Link	NP_003052 Entrez Gene 20562 MouseEntrez Gene 65047 RatEntrez Gene 6585 Human UniProt ID O75093
Background	Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene. Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions By similarity. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Synonyms	MEGF4; SLIL1; SLIT-1; SLIT3
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Axon guidance

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