KCNK3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse heart tissue IHC: 10-50 Positive control: Human brain Predicted cell location: Cytoplasm and Cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human KCNK3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45 kDa
Gene Name	potassium two pore domain channel subfamily K member 3
Database Link	NP_002237 Entrez Gene 16527 MouseEntrez Gene 29553 RatEntrez Gene 3777 Human UniProt ID O14649
Background	TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.
Synonyms	K2p3.1; OAT1; PPH4; TASK; TASK-1; TBAK1
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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