TRIM62 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: 231 and hepg2 cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human TRIM62
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54 kDa
Gene Name	tripartite motif containing 62
Database Link	NP_060677 Entrez Gene 55223 Human UniProt ID Q9BVG3
Background	TRIM62 (tripartite motif-containing 62) is a 475 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. TRIM62 contains one B box-type zinc finger, one SPRY domain and one RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. As a member of the TRIM/RBCC family, TRIM62 may function in transcriptional regulation, cell transformation and carcinogenesis. In addition, TRIM62 expression can affect the entry of murine leukemia virus (MLV) and human immunodeficiency virus 1 (HIV).
Synonyms	DEAR1
Reference Data
Protein Families	Druggable Genome

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