WNK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: TM4 cells IHC: 10-50 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human WNK1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	251 kDa
Gene Name	WNK lysine deficient protein kinase 1
Database Link	NP_061852 Entrez Gene 116477 RatEntrez Gene 232341 MouseEntrez Gene 65125 Human UniProt ID Q9H4A3
Background	This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
Synonyms	HSAN2; HSN2; KDP; p65; PPP1R167; PRKWNK1; PSK
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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