Il2 Rat Monoclonal Antibody [Clone ID: S4B6-1]

Specifications

Product Data
Clone Name	S4B6-1
Recommend Dilution	Intracellular staining, Immunohistochemstry, Immunoprecipitation, Flow cytometry, Neutralization assay, Western Blot
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	IL-2
Formulation	Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
Concentration	lot specific
Purification	Protein G chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	19.9 kDa
Gene Name	interleukin 2
Database Link	NP_032392 Entrez Gene 16183 Mouse UniProt ID P04351
Background	The rat anti-mouse IL-2 monoclonal antibody (clone S4B6-1) is of the IgG2a subtype and neutralizes both natural and recombinant mouse IL-2 in vivo (Chaudhri G. et al. 2004). Zurawski S. et al. 1986 used the S4B6-1 antibody in Western blot analysis. Their analysis showed that the determinant recognized by S4B6-1 requires the N-terminal region of mouse IL 2 and there was no cross reaction with human IL-2. The S4B6-1 antibody is also applicable in immunohistochemistry on frozen tissues, intracellular staining, FACS analysis and immunoprecipitation (Chaudhri G. et al. 2004, Assenmacher M. et al. 1998 and Mosmann T. et al. 1990).
Synonyms	aldesleukin; IL-2; interleukin-2; lymphokine; TCGF
Reference Data

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