Ki67 (MKI67) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide derived from human Ki-67 protein
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	345 & 395 kDa
Gene Name	marker of proliferation Ki-67
Database Link	NP_001139438 Entrez Gene 291234 RatEntrez Gene 4288 Human UniProt ID P46013
Background	Ki-67, a proliferation marker is a nuclear protein that is associated with and may be necessary for cellular proliferation. It can be used as a biomarker with Bcl-2 (an apoptosis inhibitor), P53 and Pax 2 for immunohistostaining in carcinomas diagnosis. The differences in the immunocytochemical expression of those markers are correlated to the results with tumor grade and stage for a further accurate diagnosis.
Synonyms	KIA; MIB-; MIB-1; PPP1R105
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS

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