GSK3 alpha (GSK3A) Rabbit Polyclonal Antibody

CAT#: TA354240

Rabbit anti GSK-3alpha Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

Product images

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Recombinant protein of human glycogen synthase kinase 3 alpha (GSK3A), 100 µg
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Specifications

Product Data
Applications WB
Recommend Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to N-terminus of human GSK3-alpha protein. This sequence is identical among human, mouse and rat.
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 52 kDa
Gene Name glycogen synthase kinase 3 alpha
Background Glycogen Synthase Kinase-3 has two isoforms, GSK-3a and GSK3β. GSK3 is a serine/threonine kinase that affects glycogen metabolism by phosphorylating and down-regulating the activity of muscle glycogen synthase as well as the regulation in Wnt signal pathway. GSK-3 alpha reduces the substrates beta-catenin and tau to imply an important role in Wnt signaling and tauopathies such as Alzheimer’s disease..
Synonyms DKFZp686D0638
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Chemokine signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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