CREB1 Rabbit Polyclonal Antibody
CAT#: TA354480
Rabbit anti CREB(pS133) Polyclonal Antibody
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CNY 4,466.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | Dot, WB |
Recommend Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to the epitope of RPSYR with a single phosphorylation site Ser133. |
Formulation | This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer. |
Purification | The Rabbit IgG is purified by site-modified Epitope Affinity Purification. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 40 kDa |
Gene Name | cAMP responsive element binding protein 1 |
Database Link | |
Background | CREB is a bZIP transcription factor that binds the cAMP response element (CRE) and activates target genes. It is involved in many extracellular signals resulting in regulation of a variety of cellular responses. Phosphorylation of CREB at Ser133 by various kinases, such as PKA, PKC, CaM kinase II and IV, is necessary for CREB signaling. |
Synonyms | CREB |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Antigen processing and presentation, Huntington's disease, Melanogenesis, Prostate cancer |
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