Sh Rabbit Polyclonal Antibody

CAT#: TA354749

Rabbit anti Shaker (Biotinylated) Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human, Drosophila
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide derived from N-terminus of Shaker protein.
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size ~73 kDa
Background The assemblage of specific ion channels and receptors at synaptic sites is crucial for signaling between pre- and post-synaptic cells. DLG (Drosophila discs-large gene) is co-localized with Shaker K1 channels, which are clustered at glutamatergic synapses. DLG-Shaker interactions are required in vivo for shaker clustering at the neuromuscular junction. The channel protein Shaker which is properly synthesized, glycosylated, folded, assembled and delivered to the plasma membrane is very important for the potassium channel function.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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