SOX9 Rabbit Polyclonal Antibody

CAT#: TA354841

Rabbit anti SOX-9 (pS181) Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

Product images

经常一起买 (4)
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Recombinant protein of human SRY (sex determining region Y)-box 9 (SOX9), 20 µg
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Recombinant protein of human SRY (sex determining region Y)-box 9 (SOX9), 100 µg
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Specifications

Product Data
Applications Dot, WB
Recommend Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide surrounding the epitope –RKSVK- with a single phosphorylation site Ser181. This sequence is identical among human, rat, mouse, bovine, chicken, and dog.
Formulation This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 56 kDa
Gene Name SRY-box 9
Background The SOX9 is a member of the SOX [Sry-related high-mobility group (HMG) box] family of HMG DNA-binding domain transcription factors and is required for the development and differentiation of multiple cell lineages. SOX9 is expressed in primary prostate cancers in vivo, at a higher frequency in recurrent prostate cancer and in prostate cancer cell lines (LNCaP, CWR22, PC3, and DU145). It has been reported that the cAMP/PKA stimulation induces SOX-9 nuclear translocation via facilitating its nuclear import by the phosphorylation of SOX-9 at Ser64 and Ser181. SOX9 in prostate basal cells supports the development and maintenance of the luminal epithelium and that a subset of prostate cancer cells may escape basal cell requirements through SOX9 expression.
Synonyms CMD1; CMPD1; SRA1; SRXX2; SRXY10
Reference Data
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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