MUC16 Mouse Monoclonal Antibody [Clone ID: OV185:1]

Specifications

Product Data
Clone Name	OV185:1
Applications	IHC
Recommend Dilution	1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	A partially purified mucin fraction from a pool of cancer tissue from patients with epithelial ovarian cancer.
Specificity	Repetitive protein determinant expressed in the protein core of the CA125 human ovarian cancer antigen
Formulation	Purified IgG fraction presented in phosphate-buffered saline (pH 7.6) with 1% bovine serum albumin carrier protein and containing 15 mM sodium azide as a preservative.
Concentration	lot specific
Purification	Purified IgG Fraction
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	mucin 16, cell surface associated
Database Link	Entrez Gene 94025 Human UniProt ID Q8WXI7
Background	CA125 antigen is usually associated with ovarian epithelial malignancies. Serum assays are widely used to detect this protein in the monitoring of ovarian cancers. CA125 antigen may also be detected by immunohistochemistry and expression has been found in neoplasms such as seminal vesicle carcinoma and anaplastic lymphoma. CA125 antigen is not found exclusively in malignant tumors. CA125 is also known as MUC16.
Synonyms	CA-125; CA125; FLJ14303; MUC-16
Reference Data

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