Cyclin D1 (CCND1) Mouse Monoclonal Antibody [Clone ID: P2D11F11]

Specifications

Product Data
Clone Name	P2D11F11
Applications	IHC
Recommend Dilution	1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic fusion protein corresponding to the human cyclin D1 molecule
Specificity	Human cyclin D1 protein
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	cyclin D1
Database Link	Entrez Gene 595 Human UniProt ID P24385
Background	The D-type cyclins are a family of proteins which function primarily by regulating the activity of cyclin dependent kinases in the G1 phase of the cell cycle. Cyclin D1, a protein of 36 kD, is also known as PRAD1 or bcl-1. Maximum expression of cyclin D1 occurs at a critical point in mid to late G1 phase of the cell cycle. The cyclin D1 gene, located on 11q13 has been reported to be overexpressed in mantle cell lymphomas due to the chromosomal translocation t(11;18).
Synonyms	BCL1; D11S287E; PRAD1; U21B31
Reference Data

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