EGFR Mouse Monoclonal Antibody [Clone ID: EGFR.113]
CAT#: TA355292
Epidermal Growth Factor Receptor Mouse Monoclonal Antibody
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CNY 22,308.00
货期*
7周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | EGFR.113 |
Applications | IHC |
Recommend Dilution | 1:20 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Prokaryotic fusion protein corresponding to the external domain of the epidermal growth factor receptor molecule |
Specificity | External domain of the human epidermal growth factor receptor |
Formulation | Liquid tissue culture supernatant containing sodium azide as a preservative |
Conjugation | Unconjugated |
Storage Condition | Store at 2-8°C |
Gene Name | epidermal growth factor receptor |
Database Link | |
Background | Epidermal growth factor receptor (EGFR) is a transmembrane protein receptor of 170 kD with tyrosine kinase activity. Increased levels of EGFR are reported to be linked with malignant transformation of squamous cells, for example, in squamous cell carcinoma of the lung, head, neck, skin, cervix and esophagus. EGFR may also play a role in the development and progression of hepatocellular carcinomas where recurrence rates are higher in EGFR-positive cases. This correlation has similarly been reported in colorectal cancers where EGFR, produced by tumor cells, plays an important role in the invasiveness and proliferation of colorectal cancers. The majority of published studies of EGFR expression in human breast cancer has similarly shown an association with EGFR expression where it is inversely related to estrogen receptor status. |
Synonyms | ERBB; ERBB1; HER1; mENA; PIG61 |
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