MelanA (MLANA) Mouse Monoclonal Antibody [Clone ID: A103]

Specifications

Product Data
Clone Name	A103
Applications	IHC
Recommend Dilution	1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant fusion protein corresponding to the human melan A molecule
Specificity	Human melan A, recognizing a 20 to 22 kD doublet in melan A mRNA-positive melanoma cell lines. Does not react with melan A mRNA_x0002_negative cell lines.
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	melan-A
Database Link	Entrez Gene 2315 Human UniProt ID Q16655
Background	Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.
Synonyms	MART-1; MART1; melan-A; OTTHUMP00000021037; OTTHUMP00000021038
Reference Data

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