PSMA (FOLH1) Mouse Monoclonal Antibody [Clone ID: 1D6]

Specifications

Product Data
Clone Name	1D6
Applications	IHC
Recommend Dilution	1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to a region within the middle of the topoisomerase I molecule
Specificity	Human topoisomerase I
Formulation	Liquid tissue culture supernatant containing sodium azide as a preservative
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	folate hydrolase (prostate-specific membrane antigen) 1
Database Link	Entrez Gene 2346 Human UniProt ID Q04609
Background	The prostate specific membrane antigen (PSMA) is expressed as a 750 amino acid glycoprotein but may also be found as PSM, a form of the protein missing the first 57 amino acids. PSMA has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase. Reports suggest that PSMA expression may correlate with tumor burden and serve as an indicator of metastatic involvement. The cellular localization of PSMA contrasts with that of prostate specific antigen (PSA) and prostatic acid phosphatase (PAP) that are secreted proteins.
Synonyms	FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Reference Data

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