Utrophin (UTRN) Mouse Monoclonal Antibody [Clone ID: DRP3/20C5]

Specifications

Product Data
Clone Name	DRP3/20C5
Applications	IHC
Recommend Dilution	1:2 - 1:10
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein containing the first 261 amino acids of the published DMDL gene sequence
Specificity	Amino terminal domain of the human homolog of human dystrophin, utrophin (also known as dystrophin related protein or "DRP”). Also crossreacts with utrophin in sections of muscle from rat and dog. Other animals species have not been tested.
Formulation	Lyophilized tissue culture supernatant containing sodium azide as a preservative.
Reconstitution Method	The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C
Gene Name	utrophin
Database Link	Entrez Gene 7402 Human UniProt ID P46939
Background	The utrophin gene is located on chromosome 6. The protein is a homologue of dystrophin and is known as dystrophin-related protein. In normal muscle, utrophin is restricted to neuromuscular junctions; however, in dystrophin-deficient muscle, utrophin expression may be upregulated and labeling appears around the periphery of most fibers. lmmunohistochemical staining with DRP2 labels vessels and neuromuscular junctions and the upregulated form of utrophin, located around fiber membranes.
Synonyms	DMDL; DRP; DRP1; FLJ23678; utrophin
Reference Data

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