SEMCAP3 (PDZRN3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of Human PDZRN3
Specificity	Expected reactivity: Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat Homology: Cow: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 100%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	80kDa
Gene Name	PDZ domain containing ring finger 3
Database Link	Entrez Gene 23024 Human UniProt ID Q9UPQ7-3
Background	PDZRN3 is an E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.
Synonyms	KIAA1095; LNX3; SEMACAP3; SEMCAP3
Reference Data

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