Memo1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish Homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 86%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	34kDa
Gene Name	mediator of cell motility 1
Database Link	NP_598532 Entrez Gene 76890 Mouse UniProt ID Q91VH6
Background	Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Synonyms	C2orf4; C21orf19-like; CGI-27; DKFZp434I0135; FLJ25031; MEMO; NS5ATP7; OTTHUMP00000201122
Reference Data

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