OGG1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Directed against isoforms 2D, 1A, 1B, 2E. Expected reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rat Homology: Cow: 93%; Dog: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 92%; Rat: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	38kDa
Gene Name	8-oxoguanine DNA glycosylase
Database Link	NP_058438 Entrez Gene 4968 Human UniProt ID O15527
Background	This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
Synonyms	HMMH; HOGG1; MMH; MUTM; OGH1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Base excision repair

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.