GPBAR1 Rabbit Polyclonal Antibody
CNY 5,250.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Specificity | Expected reactivity: Human, Rat Homology: Human: 100%; Rat: 100% |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 35kDa |
Gene Name | G protein-coupled bile acid receptor 1 |
Database Link | |
Background | This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. |
Synonyms | BG37; GPCR; GPCR19; GPR131; hBG37; hGPCR19; M-BAR; MGC40597; TGR5 |
Reference Data | |
Protein Families | Druggable Genome |
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