Adrenomedullin (ADM) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	E
Recommend Dilution	This antibody has been tested and validated in ELISA against Proadrenomedullin (1-20). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of Human Proadrenomedullin (1-20): H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2 coupled to carrier protein.
Formulation	Lyophilized whole serum. This product contains no preservative.
Reconstitution Method	Reconstitute with 50 ul of distilled water for the equivalent of undiluted antiserum.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C short term or at -20°C long term. After reconstitution store the antibody undiluted (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing.
Gene Name	adrenomedullin
Database Link	Entrez Gene 133 Human UniProt ID P35318
Background	Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂ terminal 20 peptide (PAMP). It has been suggested that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Also, PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.
Synonyms	adrenomedullin; AM; preproadrenomedullin
Reference Data

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