Cmklr1 Rat Monoclonal Antibody [Clone ID: 1G10]

Specifications

Product Data
Clone Name	1G10
Applications	IHC
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	DNA vaccine.
Specificity	Epitope: The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein.
Formulation	Affinity purified from serum-free cell culture supernatant, lyophilized. Reconstitute by adding 0.5ml distilled water. This stock solution contains 0.5mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.1% Kathon as a preservative.
Concentration	N/A
Purification	Protein G purified, lyophilized
Conjugation	Unconjugated
Storage Condition	Original vial with lyophilized antibody is stable for 1 year from date of despatch. Aliquots of stock solution can be kept frozen at -20°C for two years from date of reconstitution; do not freeze working dilutions.
Gene Name	chemokine-like receptor 1
Database Link	Entrez Gene 14747 Mouse UniProt ID P97468
Background	Monocloanl antibody 1G10 recognizes the G protein-coupled receptor CMKLR1, a member of the seven-transmembrane domain receptors. CMKLR1 is a 371 amino acid protein that binds the chemoattractant adipokine chemerin/RARRES2 and the omega-3 fatty acid derived molecule resolvin E1. Binding of the agonist leads to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. This receptor has been described to be expressed in immature plasmacytoid dendritic cells (DCs) and at lower levels in myeloid DCs, macrophages, and NK cells. Expression has also been described on macrophages isolated from different tissues.
Synonyms	CHEMERINR; ChemR23; DEZ; MGC126105; MGC126106
Reference Data

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