Kininogen 1 (KNG1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Bradykinin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	kininogen 1
Database Link	Entrez Gene 3827 Human UniProt ID P01042
Background	Bradykinin is a 9 amino acid, biologically active peptide within the kinin group of proteins that promotes inflammation. During inflammation, it is released locally from mast cells and basophils following tissue damage. It has been shown to sensitize capsaicin / temperature TRPV1 receptors, thus lowering the temperature threshold at which they activate. This antibody was generated by immunization of rabbits with Bradykinin coupled to a carrier protein.
Synonyms	BDK; bradykinin; HMWK; kininogen; KNG
Reference Data

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