TAC1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Substance P. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2 mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	0.2 mg/ml (after reconstitution)
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	tachykinin precursor 1
Database Link	Entrez Gene 6863 Human UniProt ID P20366
Background	Substance P is an undecapeptide resulting from the cleavage of Protachykinin-1 (UniProt P20366) into several biologically active peptides. It is mainly secreted by neurons and is involved in biological processes like nociception and inflammation. Substance P mediates interactions between neurons and immune cells, with nerve- derived substance P modulating immune cell proliferation and cytokine production. This antibody was generated by immunization of rabbits with Substance P coupled to a carrier protein.
Synonyms	NK2; NKA; NKNA; NPK; OTTHUMP00000204986; PPT; TAC2
Reference Data

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