Endothelin 1 (EDN1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Endothelin-3. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mouse, Rabbit, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys- Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH coupled to carrier protein.
Formulation	Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	endothelin 1
Database Link	Entrez Gene 1906 Human UniProt ID P05305
Background	Endothelin-3 (ET-3) is a member of a family of potent vasoconstrictors namely Endothelin and Sarafotoxin. It is formed by 21 amino acids and it is known as a less potent vasoconstrictor than ET-1. The two isoforms vary by 6 amino acids in sequence homology. This antibody was generated by immunization of rabbits with Endothelin-3 coupled to a carrier protein.
Synonyms	ET1; HDLCQ7; PPET1; Preproendothelin-1
Reference Data

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