ACTH (POMC) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against α-MSH. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys- Pro-Val-NH2 coupled to a carrier protein.
Formulation	Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	proopiomelanocortin
Database Link	Entrez Gene 5443 Human UniProt ID P01189
Background	Alpha-Melanocyte Stimulating Hormone (α-MSH) belongs to a group of peptide hormones also known as melanotropins. α-MSH is a neuropeptide derived from proopiomelanocortin (POMC) which is expressed in the pituitary gland and belongs to the melanocortin family. It is well known in stimulating melanin synthesis (melanogenesis) as well as in feeding behavior and energy homeostasis. Recently, it has been found that α-MSH affects immune reactions in the host for controlling inflammation in the brain and peripheral organs. This antibody was generated by immunization of rabbits with α-MSH coupled to a carrier protein.
Synonyms	ACTH; adrenocorticotropin; alpha-MSH; beta-endorphin; beta-LPH; beta-MSH; CLIP; Corticotropin-lipotropin; gamma-LPH; gamma-MSH; LPH; met-enkephalin; MSH; NPP; OTTHUMP00000119991; OTTHUMP00000200964; POC; pro-ACTH-endorphin; proopiomelanocortin
Reference Data

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