Sarafotoxin B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Sarafotoxin B. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human, Mammalian
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys- Leu-Tyr-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH coupled to carrier protein.
Formulation	Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Database Link	UniProt ID P13208
Background	Sarafotoxins (SRTXs) are group of toxins present in a venom of Atractaspis engaddensis, and in clinical trials cause similar symptoms to patients diagnosed with acute giardiasis. Together with endothelins (ETs), they form a homogenous family of strong vasoconstrictor isopeptides. The amino acid sequence comprises one sequence of 39 amino acidic residues followed by 11 sequences of 40 residues, each of it contains one SRTX sequence preceded by 19 spacer amino acids. Sarafotoxin is clinically used to act as a matrix metalloproteinase inhibitor and is useful for treating some pathological conditions including arthritis, cardiovascular diseases and tumor cell metastasis. This antibody was generated by immunization of rabbits with Sarafotoxin B coupled to a carrier protein.
Reference Data

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