DDOST Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Human bladder transitional cell carcinoma grade 2-3 tissue lysate
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human DDOST
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	51 kDa
Gene Name	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Database Link	Entrez Gene 1650 Human UniProt ID P39656
Background	This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Synonyms	AGE-R1; KIAA0115; MGC2191; OK/SW-cl.45; OST; OST48; WBP1
Reference Data

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