GNRPX (PLEKHJ1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse fetal liver tissue, Mouse heart tissue lysates IHC: 100-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human PLEKHJ1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	18 kDa
Gene Name	pleckstrin homology domain containing J1
Database Link	Entrez Gene 55111 Human UniProt ID Q9NW61
Background	PLEKHJ1 (pleckstrin homology domain containing, family J member 1), also known as GNRPX (guanine nucleotide-releasing protein x), is a 149 amino acid phosphoprotein that contains one PH (pleckstrin homology) domain and is expressed in testis and liver. The gene that encodes PLEKHJ1 maps to human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 contains the greatest gene density of the human chromosomes and is the genetic home for a number of immunoglobulin superfamily members, including killer cell and leukocyte Ig-like receptors, ICAMs, the CEACAM and PSG families, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes are also linked to chromosome 19.
Synonyms	9530063M10Rik; FLJ10297; GNRPX
Reference Data

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